1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)-
tioxazafen
CAS: 330459-31-9
Molecular Formula: C12H8N2OS
1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)- - Names and Identifiers
| Name | tioxazafen |
| Synonyms | tioxazafen Tioxazafen Solution TIOXAZAFEN SOLUTION 1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)- 3-phenyl-5-thiophen-2-yl-1,2,4-oxadiazole |
| CAS | 330459-31-9 |
1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)- - Physico-chemical Properties
| Molecular Formula | C12H8N2OS |
| Molar Mass | 228.27 |
| Density | 1.277±0.06 g/cm3(Predicted) |
| Boling Point | 390.8±34.0 °C(Predicted) |
| pKa | -1.79±0.20(Predicted) |
| Storage Condition | Room Temprature |
| Physical and Chemical Properties | EPA Chemical Information Tioxazafen (330459-31-9) |
1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)- - Upstream Downstream Industry
1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)- - Introduction
tioxazafen(tioxazafen) is an organic compound that has the following properties:
1. Appearance: tioxazafen is a colorless crystal or white to light yellow solid.
2. Solubility: tioxazafen can be well dissolved in some organic solvents, such as chloroform, ethanol and methanol.
3. Melting Point: the melting point of tioxazafen is generally in the range of 155-163 C.
4. Stability: tioxazafen is stable at room temperature, but it may react with oxidants and strong acids.
The main use of tioxazafen is as a catalyst for organic synthesis reactions. It can be used as a transition state catalyst in the reaction of benzanilide and sodium nitrite to produce related thiophene-2-carboxamides. In addition, tioxazafen can also be used to catalyze hydrogen addition reactions, asymmetric hydrogenation reactions and redox reactions.
A common method for preparing tioxazafen is to synthesize it step by step through oxidation, condensation and cyclization. The specific steps include reacting sulfuryl chloride and 2-aminoacetophenone to generate sulfimide, then condensing with sodium nitrite, and then performing an oxidation reaction to obtain the target compound.
Regarding safety information, tioxazafen has not conducted exhaustive toxicological studies. During use, appropriate protective measures should be taken, such as wearing protective gloves, glasses and protective masks, to avoid direct contact or inhalation of the compound. At the same time, it should be used in a well-ventilated place and properly stored to avoid reaction with other chemicals. If ingestion or contact with skin, please seek medical help as soon as possible.
1. Appearance: tioxazafen is a colorless crystal or white to light yellow solid.
2. Solubility: tioxazafen can be well dissolved in some organic solvents, such as chloroform, ethanol and methanol.
3. Melting Point: the melting point of tioxazafen is generally in the range of 155-163 C.
4. Stability: tioxazafen is stable at room temperature, but it may react with oxidants and strong acids.
The main use of tioxazafen is as a catalyst for organic synthesis reactions. It can be used as a transition state catalyst in the reaction of benzanilide and sodium nitrite to produce related thiophene-2-carboxamides. In addition, tioxazafen can also be used to catalyze hydrogen addition reactions, asymmetric hydrogenation reactions and redox reactions.
A common method for preparing tioxazafen is to synthesize it step by step through oxidation, condensation and cyclization. The specific steps include reacting sulfuryl chloride and 2-aminoacetophenone to generate sulfimide, then condensing with sodium nitrite, and then performing an oxidation reaction to obtain the target compound.
Regarding safety information, tioxazafen has not conducted exhaustive toxicological studies. During use, appropriate protective measures should be taken, such as wearing protective gloves, glasses and protective masks, to avoid direct contact or inhalation of the compound. At the same time, it should be used in a well-ventilated place and properly stored to avoid reaction with other chemicals. If ingestion or contact with skin, please seek medical help as soon as possible.
Last Update：2024-04-09 21:11:58
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Product Name: Tioxazafen Visit Supplier Webpage Request for quotation
CAS: 330459-31-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 330459-31-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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Raw Materials for 1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)-